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S6389

1-Stearoyl-2-arachidonoyl-sn-glycerol

Name: 1-Stearoyl-2-arachidonoyl-<I>sn</I>-glycerol
Brand: SIGMA

~98%, suitable for stimulation of protein kinase C derived from liver cells, liquid

Synonym(s):

1-Octadecanoyl-2-([cis,cis,cis,cis]-5,8,11,14-eicosatetraenoyl)-sn-glycerol, 2-Arachidonoyl-1-stearoyl-sn-glycerol

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About This Item

Empirical Formula (Hill Notation):

C₄₁H₇₂O₅

CAS Number:

65914-84-3

Molecular Weight:

645.01

PubChem Substance ID:

24899699

UNSPSC Code:

41106305

Beilstein/REAXYS Number:

2198923

MDL number:

MFCD00070361

Assay:

~98%

Form:

liquid

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Properties

assay

~98%

form

liquid

impurities

1,3-isomer, trace

solubility

chloroform: 20 mg/ml

suitability

suitable for stimulation of protein kinase C derived from liver cells

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC

InChI

1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3/b13-11-,19-17-,24-22-,30-28-

InChI key

NSXLMTYRMFVYNT-LGHBDAFPSA-N

Description

Application

1-Stearoyl-2-arachidonoyl-sn-glycerol was used to study Ca⁺² signaling.^5,6

Biochem/physiol Actions

1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacyl glycerol (DAG) that allosterically activates PKC and other proteins that affect cell growth, development, survival, apoptosis, carcinogenesis and metastasis.³ It activates transient receptor potential channels 3 and 6 that regulates the intracellular free calcium levels.⁴

Packaging

Sealed ampule

Disclaimer

This material may isomerize during storage.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c