S6444
N-Salicyloyltryptamine
≥98% (HPLC), solid
Synonym(s):
2-Hydroxy-N-[2-(1H-indol-3-yl)ethyl]benzamide, STP
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About This Item
Empirical Formula (Hill Notation):
C17H16N2O2
CAS Number:
Molecular Weight:
280.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
assay
≥98% (HPLC)
form
solid
color
white
solubility
DMSO: ~26 mg/mL
storage temp.
2-8°C
SMILES string
Oc1ccccc1C(=O)NCCc2c[nH]c3ccccc23
InChI
1S/C17H16N2O2/c20-16-8-4-2-6-14(16)17(21)18-10-9-12-11-19-15-7-3-1-5-13(12)15/h1-8,11,19-20H,9-10H2,(H,18,21)
InChI key
XBPYTDZHCNJRBY-UHFFFAOYSA-N
Biochem/physiol Actions
N-Salicyloyltryptamine (STP) is a central nervous system depressant that inhibits the transient outward and sustained K+ current in neuroendocrine cells. This decreases the ability of neuronal cells to generate action potential.1,3 STP is has immunomodulatory effects as it inhibits the activation of ERK 1/2 and NF-κB.4
Activator of calcium-activated K+ channels; anticonvulsant and neuroprotectant.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| S6444-25MG | 04061832274119 |
| S6444-5MG | 04061832575902 |
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