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Merck
CN

S6561

Anti-Sodium Channel, Brain Type II (α Subunit) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-BII, Anti-SP11II

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About This Item

UNSPSC Code:
12352203
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (f), IP, WB CL
Citations:
1
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, mouse

technique(s)

immunohistochemistry (frozen sections): 1:75 using using frozen brain tissue, immunoprecipitation (IP): suitable, western blot (chemiluminescent): 1:150-1:300

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Scn2a1(110876)
rat ... Scn2a1(24766)

Immunogen

synthetic peptide corresponding to amino acids 467-485 of the α subunit of rat type II voltage-gated sodium channel (VGSC, SP11II) with additional N-terminal lysine and tyrosine, conjugated to KLH. The epitope corresponds to the sequence in the intracellular loop between the I and II domains of type II VGSC α subunit.

Physical form

Lyophilized at ~0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.


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Related Content


M Noda et al.
Nature, 322(6082), 826-828 (1986-08-03)
The voltage-gated sodium channel is a transmembrane protein essential for the generation of action potentials in excitable cells. It has been reported that sodium channels purified from the electric organ of the electric eel, Electrophorus electricus, and from chick cardiac



Global Trade Item Number

SKUGTIN
S6561-.2ML04061835809851