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Merck
CN

S7143

Sodium thiosulfate pentahydrate

ACS reagent, pH 6.0-8.4 (25 °C, 5% in solution), 99.5-101.0%

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About This Item

Linear Formula:
Na2S2O3 · 5H2O
CAS Number:
10102-17-7
Molecular Weight:
248.18
EC Number:
231-867-5
UNSPSC Code:
12352200
MDL number:
MFCD00149186

Key Documents

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InChI key

PODWXQQNRWNDGD-UHFFFAOYSA-L

InChI

1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2

SMILES string

O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=S

grade

ACS reagent

assay

99.5-101.0%

impurities

≤0.002% Nitrogen compounds (as N), ≤0.005% Insoluble matter

pH

6.0-8.4 (25 °C, 5% in solution)

anion traces

sulfate, sulfite (as SO42-): ≤0.1%, sulfide (S2-): passes test (limit about 1 ppm)

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wgk

WGK 1

Storage Class

13 - Non Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
128H0162
124H0193
110K0241
108H0142
108F0055

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Michael C Reade et al.
Emergency medicine Australasia : EMA, 24(3), 225-238 (2012-06-08)
Cyanide poisoning is uncommon, but generates interest because of the presumed utility of an antidote immediately available in those areas with a high risk of cyanide exposure. As part of its regular review of guidelines, the Australian Resuscitation Council conducted
Brooke Bair et al.
Journal of drugs in dermatology : JDD, 10(9), 1042-1044 (2011-11-05)
Calcinosis cutis is a term used to describe a group of disorders which result in calcium deposits in the skin. These disorders can be separated based on etiology. Sodium thiosulfate has been used to systemically treat calciphylaxis with little to
Melani Sooriyaarachchi et al.
Metallomics : integrated biometal science, 5(3), 197-207 (2013-02-28)
Cis-Platin (CP) is a remarkably effective Pt-based anticancer drug, but it also exhibits severe toxic side-effects, including nephrotoxicity and ototoxicity. Previous studies conducted with mammalian model organisms have clearly demonstrated that the intravenous administration of N-acetyl-L-cysteine (NAC) or sodium thiosulfate
Bita Arabshahi et al.
The Journal of pediatrics, 160(3), 520-522 (2012-01-17)
We report the successful use of abatacept and sodium thiosulfate in a patient with severe recalcitrant juvenile dermatomyositis complicated by ulcerative skin disease and progressive calcinosis. This combination therapy resulted in significant reductions in muscle and skin inflammation, decreased corticosteroid
Vikhyat S Bebarta et al.
Annals of emergency medicine, 59(6), 532-539 (2012-03-06)
We compare the efficacy of hydroxocobalamin to sodium thiosulfate to reverse the depressive effects on mean arterial pressure in a swine model of acute cyanide toxicity and gain a better understanding of the mechanism of action of the hydroxocobalamin in
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