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Merck
CN

S7144

Sera, abnormal (deficient) human

Triiodothyronine/thyroxine (T3/T4)-deficient

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About This Item

UNSPSC Code:
12352207
MDL number:
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biological source

human

description

essentially lipid-free, lyophilized from the indicated amount of serum.

composition

T4 level, <4 μg/L RIA

storage temp.

2-8°C

Application

Triiodothyronine/thyroxine deficient human serum may be useful in studies on the effects of thyroid hormones on cell signaling, differentiation and survival in cell culture.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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David M Selva et al.
Journal of molecular endocrinology, 43(1), 19-27 (2009-04-02)
Thyroid hormones increase hepatic sex hormone-binding globulin (SHBG) production, which is also regulated by hepatocyte nuclear factor-4alpha (HNF-4alpha) in response to changes in the metabolic state of the liver. Since the human SHBG promoter lacks a typical thyroid hormone response
Jinhua Dong et al.
Biosensors & bioelectronics, 165, 112425-112425 (2020-07-31)
Quenchbody (Q-body) is a fluorescent biosensor in which a fluorescent dye is tagged near the antigen binding site of an antibody. The fluorescence of the dye is quenched by the tryptophan residues present in the variable region of the antibody