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S7563

β-Sheet Breaker Peptide

Name: β-Sheet Breaker Peptide
Brand: SIGMA

>95% (HPLC), solid

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About This Item

Empirical Formula (Hill Notation):

C₅₁H₈₁N₁₃O₁₆

Molecular Weight:

1132.27

UNSPSC Code:

12352200

MDL number:

MFCD03093422

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Properties

assay

>95% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](C)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H]4CCCN4C(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(O)=O

Description

Biochem/physiol Actions

Reverses prion protein (PrP) conformational changes implicated in the pathogenesis of spongiform encephalopathies.

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

042K1953

091K1184

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Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle.

K Højlund et al.

Diabetologia, 53(3), 541-551 (2009-12-17)

Insulin resistance in skeletal muscle is linked to mitochondrial dysfunction in obesity and type 2 diabetes. Emerging evidence indicates that reversible phosphorylation regulates oxidative phosphorylation (OxPhos) proteins. The aim of this study was to identify and quantify site-specific phosphorylation of