Name: Salvinorin A
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₈O₈

CAS Number:

83729-01-5

Molecular Weight:

432.46

MDL number:

MFCD05664742

UNSPSC Code:

12352200

PubChem Substance ID:

24899776

NACRES:

NA.77

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Quality Level

100

Assay

≥98% (HPLC)

form

solid

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

storage condition

protect from light

color

white

solubility

DMSO: ≥10 mg/mL
ethanol: ~3 mg/mL

storage temp.

−20°C

SMILES string

[H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OC(C)=O)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c4ccoc4)C(=O)OC

InChI

1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1

InChI key

OBSYBRPAKCASQB-AGQYDFLVSA-N

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)
rat ... Oprk1(29335)

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Application

Salvinorin A was administered to rats to study effects on lactic acid-stimulated stretching.¹

Biochem/physiol Actions

Salvanorin A is a non-nitrogenous κ opioid receptor agonist.

Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (K_i=4.3 nm) and cloned (K_i=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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