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S8076

Sigma-Aldrich

SJ000025081

≥98% (HPLC)

Synonym(s):

7-(3,4-Dimethoxyphenyl)-4-(2-fluorophenyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-3-quinolinecarboxylic acid propyl ester

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About This Item

Empirical Formula (Hill Notation):
C28H30FNO5
CAS Number:
Molecular Weight:
479.54
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

pale yellow

solubility

DMSO: ≥40 mg/mL

storage temp.

2-8°C

SMILES string

CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3F)C(=O)CC(C2)c4ccc(OC)c(OC)c4

InChI

1S/C28H30FNO5/c1-5-12-35-28(32)25-16(2)30-21-13-18(17-10-11-23(33-3)24(15-17)34-4)14-22(31)27(21)26(25)19-8-6-7-9-20(19)29/h6-11,15,18,26,30H,5,12-14H2,1-4H3

InChI key

JYAOIVVCGRSAFZ-UHFFFAOYSA-N

Application

SJ000025081 may be used in studies related to malarial parasite and immune signaling.

Biochem/physiol Actions

SJ000025081 is a dihydropyridine effective against Plasmodium yoelii.1,2
SJ000025081 is an antimalarial compound that inhibit the growth of asexual blood-stage P. falciparum in cultured red blood cells.
SJ000025081 is an antimalarial compound.

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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