Skip to Content
Merck
CN

Key Documents

View All Documentation

S8251

Succinylcholine chloride dihydrate

98.0-102.0%, Cholinergic antagonist, solid

Synonym(s):

Bis(trimethylammonioethyl) succinate chloride, Succinyldicholine dichloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
[(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
CAS Number:
6101-15-1
Molecular Weight:
397.34
NACRES:
NA.77
PubChem Substance ID:
24277873
UNSPSC Code:
41116107
EC Number:
200-747-4
MDL number:
MFCD00150564
Beilstein/REAXYS Number:
3922827
Assay:
98.0-102.0%
Form:
solid
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Succinylcholine chloride dihydrate, 98.0-102.0%, solid

Quality Segment

100

assay

98.0-102.0%

form

solid

color

white

solubility

H2O: complete 100 mg/ml, clear to slightly hazy, colorless, H2O: soluble (unstable at pH > 9.)

originator

Novartis

SMILES string

O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C

InChI

1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2

InChI key

FFSBEIRFVXGRPR-UHFFFAOYSA-L

Application

Succinylcholine chloride dehydrate was used to study the mechanism of gating of Cys loop receptors in Xenopus laevis.4,5

Biochem/physiol Actions

Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.
Succinylcholine is a cholinergic antagonist and a neuromuscular blocking agent. It induces depolarization of acetylcholine receptors on the muscle membrane and efflux of potassium from the muscle that leads to hypokalemia in individuals with upregulated expression of acetylcholine receptors.3

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Solutions may be stored for several days at 4 °C.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library