S8432
Sulfo NONOate disodium salt
Synonym(s):
Hydroxydiazenesulfonic acid 1-oxide disodium salt
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About This Item
Linear Formula:
N2O5SNa2
Molecular Weight:
186.06
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
form
powder
shipped in
dry ice
storage temp.
−70°C
SMILES string
[Na+].[Na+].[O-]\N=[N+](/[O-])S([O-])(=O)=O
InChI
1S/H2N2O5S.2Na/c3-1-2(4)8(5,6)7;;/h3H,(H,5,6,7);;/q;2*+1/p-2/b2-1+;;
InChI key
LYIIGAIVRHASTQ-SEPHDYHBSA-L
Application
Does not release NO; useful as a negative control in NONOate research
Biochem/physiol Actions
SKI 5C was used to inhibit Sphingosine kinase 1 in SK-Hep1, HEK-293T cells.1
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Aneta Balcerczyk et al.
Free radical biology & medicine, 39(3), 327-335 (2005-07-05)
The specificity of 4-amino-5-methylamino-2',7'-difluorofluorescein (DAF-FM) for nitric oxide was evaluated in in vitro systems. The probe was found fairly specific for nitric oxide. Potential sources of artifacts include the autoxidation of DAF-FM, potentiated by light, and its oxidation by sources
C M Maragos et al.
Journal of medicinal chemistry, 34(11), 3242-3247 (1991-11-01)
Selected nucleophile/nitric oxide adducts [compounds which contain the anionic moiety, XN(O-)N = O] were studied for their ability to release nitric oxide spontaneously in aqueous solution and for possible vasoactivity. The diversity of structures chosen included those in which the
Articles
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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