Skip to Content
Merck
CN

S8627

Sulfacetamide

≥98.0%

Synonym(s):

N-(4-Aminobenzenesulfonyl)acetamide, N-(4-Aminophenylsulfonyl)acetamide, N1-Acetylsulfanilamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C8H10N2O3S
CAS Number:
144-80-9
Molecular Weight:
214.24
UNSPSC Code:
51283901
NACRES:
NA.85
PubChem Substance ID:
24899803
EC Number:
205-640-6
Beilstein/REAXYS Number:
981718
MDL number:
MFCD00066501

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)

InChI key

SKIVFJLNDNKQPD-UHFFFAOYSA-N

SMILES string

CC(=O)NS(=O)(=O)c1ccc(N)cc1

assay

≥98.0%

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycoplasma

mode of action

DNA synthesis | interferes

Looking for similar products? Visit Product Comparison Guide

Application

Sulfacetamide is used to study the treatment of acne and seborrheic dermatitis. It is used to study neonatal chlamydial conjunctivitis and meningococcal conjunctivitis.

Biochem/physiol Actions

Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

General description

Chemical structure: sulfonamide

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids

Packaging

100G,500G

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317,H335

Hazard Classifications

Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
049M4875V
048M4880V
018M4814V
067M4812V
106M4767V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

SODIUM SULFACETAMIDE FOR SEBORRHEIC DERMATITIS
STEPHEN T. WHELAN
American Journal of Diseases of Children, 71, 724-724 (1955)
Demet Sensoy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(3), 487-495 (2009-02-19)
The aim of this study was to prepare bioadhesive sulfacetamide sodium (SA) microspheres to increase their residence time on the ocular surface and to enhance their treatment efficacy on ocular keratitis. Microspheres were fabricated by spray drying method using mixture
E Kremer et al.
Journal of inorganic biochemistry, 100(7), 1167-1175 (2006-04-06)
The synthesis, characterization and comparative biological study of a series of antibacterial copper complexes with heterocyclic sulfonamides were reported. Two kinds of complexes were obtained with the stoichiometries [Cu(L)2] . H2O and [Cu(L)2(H2O)4] . nH2O. They were characterized by infrared
Rade Injac et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(4), 424-431 (2008-03-19)
A separation technique for zinc bacitracin, polymyxin B, oxytetracycline and sulfacetamide in animal feedstuffs by micellar electrokinetic capillary chromatography (MEKC) was developed. The running buffer was 20 mmol l(-1) borate, 20 mmol l(-1) phosphate, pH 8.4, containing 20 mmol l(-1)
Fatmah A M Al-Omary et al.
Bioorganic & medicinal chemistry, 18(8), 2849-2863 (2010-03-31)
A new series of 2,6-substituted-quinazolin-4-ones was designed, synthesized, and evaluated for their in vitro DHFR inhibition, antimicrobial, and antitumor activities. Compounds 22, 33-37, 39-43, and 45 proved to be active DHFR inhibitors with IC(50) range of 0.4-1.0microM. Compound 18 showed
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service