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About This Item
Empirical Formula (Hill Notation):
C13H13N3O5S2
CAS Number:
Molecular Weight:
355.39
Beilstein:
349989
EC Number:
MDL number:
UNSPSC Code:
51283905
PubChem Substance ID:
Assay
≥98%
form
powder
color
white to off-white
solubility
1 M NaOH: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
Mode of action
DNA synthesis | interferes
enzyme | inhibits
SMILES string
OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
InChI
1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
InChI key
SKVLYVHULOWXTD-UHFFFAOYSA-N
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General description
Chemical structure: sulfonamide
Application
Succinylsulfathiazole is used to block the synthesis of folic acid. It is used to study folate deficiency. It is used to suppress folate production by bacteria in the intestine.
Biochem/physiol Actions
Succinylsulfathiazole is a competitive inhibitor of dihydropteroate synthetase. It is a dihydrofolate reductase (DHFR) inhibitor.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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