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Merck
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SAB1300356

Anti-Drosophila Dj-1b (N-term) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

Synonym(s):

Anti-CG1349-PA, Anti-DJ-1 β, Anti-Dj-1 β, Anti-Dj-1-β, Anti-GH09983p

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

Drosophila

technique(s)

indirect ELISA: 1:1000, western blot: 1:100-1:500

NCBI accession no.

NP_651825

UniProt accession no.

Q9VA37

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

Drosophila melanogaster ... Dj-1Beta(43652)

General description

DJ-1 mutations are associated with rare forms of autosomal recessive early-onset Parkinson′s disease (PD). DJ-1 is suggested to normally function as a redox-sensitive molecular chaperone protective against cellular oxidative stress. DJ-1 Drosophila models are an important tool for elucidating protein function and for modeling neurodegenerative disease.

Immunogen

DJ-1B (NP_651825, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Drosophila DJ-1B.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
020M2226

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Diana A Quintero-Espinosa et al.
Neurochemical research, 49(9), 2440-2452 (2024-06-07)
Parkinson's disease (PD) is a complex multifactorial progressive neurodegenerative disease characterized by locomotor alteration due to the specific deterioration of dopaminergic (DAergic) neurons in the substantia nigra pars compacta (SNpc). Mounting evidence shows that human LRRK2 (hLRRK2) kinase activity is

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