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Merck
CN

SAB1300547

Anti-PSMA5 (center) antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-Macropain ζ chain, Anti-PSMA5, Anti-Proteasome ζ chain, Anti-Proteasome subunit α type-5, Multicatalytic endopeptidase complex ζ chain

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC, WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000, western blot: 1:100-1:500

NCBI accession no.

NP_002781

UniProt accession no.

P28066

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PSMA5(14029)

General description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.

Immunogen

PSMA5 (NP_002781, 111-145)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PSMA5.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
010M1648

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