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Merck
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SAB1300718

Anti-Phospho-APBB1-S347 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-APBB1, Anti-Amyloid β A4 precursor protein-binding family B member 1, Anti-FE65, Anti-Fe65 protein

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: 1:1000, western blot: 1:100-1:500

NCBI accession no.

NP_001155.1

UniProt accession no.

O00213

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer347)

Gene Information

human ... APBB1(322)

Related Categories

General description

APBB1 is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer′s disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product′s nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer′s disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression.

Immunogen

APBB1 (NP_001155.1, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S347 of human APBB1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
010M0528

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