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Key Documents

SAB1300726

Sigma-Aldrich

Anti-Phospho-SLAMF1-pY281 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CD150 antigen, Anti-CDw150, Anti-IPO-3, Anti-SLAMF1, Anti-Signaling lymphocytic activation molecule [Precursor]

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

dot blot: suitable
indirect ELISA: 1:1000

NCBI accession no.

NP_003028

UniProt accession no.

Q13291

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr281)

Gene Information

human ... SLAMF1(6504)

General description

SLAMF1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

Immunogen

SLAMF1 (NP_003028, 264-296)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y281 of human SLAMF1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
010M1761

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