SAB1300755
Anti-HIRA (center) antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
Synonym(s):
Anti-DGCR1, Anti-HIR, Anti-TUP1-like enhancer of split protein 1, Anti-TUPLE1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
conjugate
unconjugated
antibody form
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HIRA(7290)
General description
HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Immunogen
HIRA (NP_003316, 436-471)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HIRA.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HIRA.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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