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Merck
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SAB1300978

Sigma-Aldrich

Anti-DGKI (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000

NCBI accession no.

NP_004708

UniProt accession no.

O75912

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DGKI(9162)

Related Categories

Immunogen

DGKI (139-174)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DGKI.

Application

Anti-DGKI (N-term) antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:50-1:100 and indirect ELISA at a dilution of 1:1000.

Biochem/physiol Actions

DGKI (Diacylglycerol kinase iota) is mainly involved in the maintenance of intracellular concentration of diacylglycerol by phosphorylating other lipids in addition to DAG. DGKI has been predicted to be a potential gene for tumor suppression in colorectal cancers and mutation in DGKI has been linked to the melanoma.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
010M1741

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The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking ??-Catenin/TCF Regulated Transcription
Gastroenterology Research and Practice (2016)
The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking ??-Catenin/TCF Regulated Transcription
Wael M. Abdel-Rahman, et al.
Gastroenterology Research and Practice (2016)
Matthew K Topham et al.
Biochimica et biophysica acta, 1790(6), 416-424 (2009-04-15)
The mammalian diacylglycerol kinases (DGK) are a group of enzymes having important roles in regulating many biological processes. Both the product and the substrate of these enzymes, i.e. diacylglycerol and phosphatidic acid, are important lipid signalling molecules. Each DGK isoform

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