SAB1300978
Anti-DGKI (N-term) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DGKI(9162)
Immunogen
DGKI (139-174)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DGKI.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DGKI.
Application
Anti-DGKI (N-term) antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:50-1:100 and indirect ELISA at a dilution of 1:1000.
Biochem/physiol Actions
DGKI (Diacylglycerol kinase iota) is mainly involved in the maintenance of intracellular concentration of diacylglycerol by phosphorylating other lipids in addition to DAG. DGKI has been predicted to be a potential gene for tumor suppression in colorectal cancers and mutation in DGKI has been linked to the melanoma.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking ??-Catenin/TCF Regulated Transcription
Gastroenterology Research and Practice (2016)
The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking ??-Catenin/TCF Regulated Transcription
Wael M. Abdel-Rahman, et al.
Gastroenterology Research and Practice (2016)
Matthew K Topham et al.
Biochimica et biophysica acta, 1790(6), 416-424 (2009-04-15)
The mammalian diacylglycerol kinases (DGK) are a group of enzymes having important roles in regulating many biological processes. Both the product and the substrate of these enzymes, i.e. diacylglycerol and phosphatidic acid, are important lipid signalling molecules. Each DGK isoform
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