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Merck
CN

SAB1407449

Sigma-Aldrich

Anti-CERCAM antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

CEECAM1, GLT25D3, MGC149620, MGC149621

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~59.1 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

NM_016174.3

UniProt accession no.

Q5T4B2

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CERCAM(51148)

General description

CERCAM (Cerebral endothelial cell adhesion molecule) is a cell adhesion protein highly expressed in secretory tissues like salivary glands, pancreas, and placenta, and in the nervous system.
Mouse polyclonal antibody raised against a full-length human CERCAM protein.

Immunogen

CERCAM (NP_057258.2, 1 a.a. ~ 517 a.a) full-length human protein.

Sequence
MLQEWLAAVGDDYAAVVWRPEGEPRFYPDEEGPKHWTKERHQFLMELKQEALTFARNWGADYILFADTDNILTNNQTLRLLMGQGLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRRGCFRVPMVHSTFLASLRAEGADQLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNEHRYGYMNVPVKSHQGLEDERVNFIHLILEALVDGPRMQASAHVTRPSKRPSKIGFDEVFVISLARRPDRRERMLASLWEMEISGRVVDAVDGWMLNSSAIRNLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVARGLARVLVFEDDVRFESNFRGRLERLMEDVEAEKLSWDLIYLGRKQVNPEKETAVEGLPGLVVAGYSYWTLAYALRLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLVAFSAQPLLAAPTHYAGDAEWLSDTETSSPWDDDSGRLISWSGSQKTLRSPRLDLTGSSGHSLQPQPRDEL

Application

Anti-CERCAM antibody produced in mouse is suitable for western blot analysis.

Biochem/physiol Actions

CERCAM (Cerebral endothelial cell adhesion molecule) functions as a carbohydrate-binding protein at the cell surface. It is involved in leukocyte transmigration across the blood-brain barrier.

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
08295

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Belinda Schegg et al.
Molecular and cellular biology, 29(4), 943-952 (2008-12-17)
Collagen is a trimer of three left-handed alpha chains representing repeats of the motif Gly-X-Y, where (hydroxy)proline and (hydroxy)lysine residues are often found at positions X and Y. Selected hydroxylysines are further modified by the addition of galactose and glucose-galactose
R M Starzyk et al.
The Journal of infectious diseases, 181(1), 181-187 (1999-12-23)
The tight junctions of the cerebral capillary endothelium form the highly restrictive blood-brain barrier. Migration of leukocytes across this unique barrier may involve ligation of elements in addition to those of the fenestrated capillaries of the peripheral vascular system. An

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