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SAB1411546

Sigma-Aldrich

Anti-ASMTL antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

Synonym(s):

ASMTLX, ASMTLY, ASTML

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 68.8 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

BC002508

UniProt accession no.

O95671

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ASMTL(8623)

Related Categories

General description

ASMTL (Acetylserotonin O-methyltransferase-like) is a novel gene located in the pseudoautosomal region (PAR1) of the human X and Y chromosomes. It has a bipartite structure expressed in pancreas, placenta, colon, fibroblast and fetal brain tissues. Its C-terminal end possesses structural homology with N-acetylserotonin O-methyltransferase and N-terminal end has the similarity with multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli. ASMTL encodes the enzyme catalysing the last step in the synthesis of melatonin.

Immunogen

ASMTL (AAH02508.1, 1 a.a. ~ 621 a.a) full-length human protein.

Sequence
MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSKVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
10146

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K Ried et al.
Human molecular genetics, 7(11), 1771-1778 (1998-09-16)
We have isolated a novel gene, ASMTL (acetylserotonin methytransferase-like ), in the pseudoautosomal region (PAR1) on the human sex chromosomes. ASMTL represents a unique fusion product of two different full-length genes of different evolutionary origin and function. One part is

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