Skip to Content
Merck
CN

SAB2500030

Anti-Adenosine A2B Receptor antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-ADORA2, Anti-ADORA2B, Anti-HGNC:264, Anti-Netrin-1 receptor

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02095793
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, FACS, IF, IHC
Citations:
6

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

ELISA: suitable, flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable

UniProt accession no.

P29275

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ADORA2B(136)

General description

ADORA2B (adenosine A2b receptor) is a G-protein coupled receptor. It is the most adenosine insensitive adenosine receptor. This gene is located on human chromosome 17p12-p11.2.

Immunogen

Peptide with sequence CQADVKSGNGQ from the C Terminus of the protein sequence according to NP_000667.1.

Biochem/physiol Actions

ADORA2B (adenosine A2b receptor) acts as a therapeutic target for cancer treatment. The tumor cells can use A2b receptor to induce progression. ADORA2B controls immune cell activity. It plays a major role in the transcriptional induction and protein stability of protein period 2 (Per2).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

含少量动物源组分生物产品
常规特殊物品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
6936S2
6936P1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.
Eckle T, et al.
Nature Medicine, 18(5), 774?782-774?782 (2012)
Role of adenosine A2b receptor overexpression in tumor progression.
Sepulveda C, et al.
Life Sciences, 166, 92-99 (2016)
Linya Wang et al.
PloS one, 19(6), e0301223-e0301223 (2024-06-05)
New immune checkpoints are emerging in a bid to improve response rates to immunotherapeutic drugs. The adenosine A2A receptor (A2AR) has been proposed as a target for immunotherapeutic development due to its participation in immunosuppression of the tumor microenvironment. Blockade
Pharmacogenetics of asthma.
Fenech A and Hall IP
British Journal of Clinical Pharmacology, 53(1), 3-15 (2002)
The A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism.
M?lck C, et al.
Cancer Letters, 383(1), 135-143 (2016)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service