SAB2500149
Anti-BAK1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-BAK, Anti-BCL2-antagonist/killer 1, Anti-BCL2L7, Anti-CDN1
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
4
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... BAK1(578)
General description
BCL2 antagonist/killer 1 (BAK1) is part of the BCL-2 family of apoptosis regulators. It is a pro-apoptotic protein. The gene encoding BAK1 is localized on human chromosome 6p21.33.
Immunogen
Peptide with sequence ASGQGPGPPRQE-C from the N Terminus of the protein sequence according to NP_001179.
Biochem/physiol Actions
BCL2 antagonist/killer 1 (BAK1) modulates the lifespan of platelets. It has been associated with dengue hemorrhagic fever. BAK1 promotes the opening of the mitochondrial voltage-dependent anion channel and aids the release of cytochrome c.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia
Susan L
Blood (2012)
Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever.
Dang TN
BMC Medical Genetics (2016)
Putative roles of mitochondrial Voltage-Dependent Anion Channel, Bcl-2 family proteins and c-Jun N-terminal Kinases in ischemic stroke associated apoptosis
Rajeev Gupta
Biochimie (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB2500149-100UG | 04061832482651 |