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Merck
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SAB2500750

Anti-PARK7/DJ-1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-DJ1, Anti-Oncogene DJ1, Anti-Parkinson disease (autosomal recessive)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
6
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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, mouse, human

technique(s)

indirect ELISA: suitable, western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PARK7(11315)

Immunogen

Peptide with sequence C-AAQVKAPLVLKD from the C Terminus of the protein sequence according to NP_009193.

Application

Anti-PARK7/DJ-1 antibody produced in goat is suitable for indirect ELISA and western blot.

Biochem/physiol Actions

PARK7 is a member of novel glyoxalase family. It exerts mitochondrial activity. It has been suggested that PARK7 may act as an antioxidant and/or a molecular chaperone. It may also detoxify aggressive metabolic aldehyde by-products. It helps in stabilizing mitochondria during cellular stress. Alteration in gene function affects neurodegeneration, which leads to the autosomal recessive early-onset parkinsonism.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Larissa Berloffa Belardin et al.
Journal of assisted reproduction and genetics, 33(12), 1657-1664 (2016-09-16)
To verify if the presence of varicocele (grades II and III) with and without seminal alterations, using the 5 This cross sectional study was performed at the Sao Paulo Federal University Paulo between May 2014 and April 2016. A total
Yusuke Toyoda et al.
Biology open, 3(8), 777-784 (2014-07-27)
Parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of the substantia nigra. One of the genes linked with the onset of Parkinson's disease, DJ-1/PARK7, belongs to a novel glyoxalase family and influences mitochondrial activity. It has been assumed
L Belardin et al.
Andrology, 7(1), 53-61 (2018-10-26)
Cysteine-rich secretory protein (CRISP-3), a protein involved in inflammatory response, is highly increased in seminal plasma of adolescents with varicocoele and altered semen analysis, but not in adolescents with varicocoele and normal semen. It is not known, however, whether this



Global Trade Item Number

SKUGTIN
SAB2500750-100UG04061832485300