biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
flow cytometry: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PCK2(5106)
General description
The gene encoding phosphoenolpyruvate carboxykinase 2, mitochondrial (PEPCK-M) or PCK2 is localized on human chromosome 14q11.2–q12.
Immunogen
Peptide with sequence KPWKPGDKEPCAH from the internal region of the protein sequence according to NP_004554.2.
Biochem/physiol Actions
Phosphoenolpyruvate carboxykinase 2, mitochondrial (PEPCK-M) or PCK2 has a role in gluconeogenesis and TCA cycle. It converts oxaloacetate to phosphoenolpyruvate. Elevated levels of this protein are observed in non-small-cell lung carcinoma (NSCLC).
Features and Benefits
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Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
Emma E.Vincent
Molecular Cell (2015)
Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene
Said Modaressi
The Biochemical Journal (1998)
PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth.
Molecular Cell (2015)
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