SAB2501718
Anti-COPS3 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
Synonym(s):
COP9 complex subunit 3, COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis), CSN3, SGN3
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
2
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, canine, mouse, rat, bovine
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... COPS3(8533)
General description
COPS3 (COP9 signalosome subunit 3) encodes the third subunit of an eight-subunit complex, the COP9 signalosome (CSN), and is located on chromosome 17p11.2.
Immunogen
Peptide with sequence C-SLYKKNIQRLT, from the internal region of the protein sequence according toNP_003644.2
Application
Anti-COPS3 antibody produced in goat is suitable for indirect ELISA and western blot applications.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Inhibition of Csn3 expression induces growth arrest and apoptosis of hepatocellular carcinoma cells.
Yong-sheng Yu et al.
Cancer chemotherapy and pharmacology, 69(5), 1173-1180 (2012-01-13)
Csn3 (or CSN3) encodes the third subunit of an eight-subunit complex, the COP9 signalosome (CSN), which acts as a protein kinase and a deneddylase in mammalian cells. Previous studies have shown that Csn3 is essential for maintenance of cell proliferation
Joeri Both et al.
PloS one, 7(1), e30907-e30907 (2012-02-01)
Osteosarcoma is the most common primary malignancy of bone. The tumours are characterized by high genomic instability, including the occurrence of multiple regions of amplifications and deletions. Chromosome region 17p11.2-p12 is amplified in about 25% of cases. In previous studies
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB2501718-100UG | 04061831452549 |