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Merck
CN

SAB2701992

Anti-EPAS1 antibody produced in rabbit

Synonym(s):

HLF, MOP2, PASD2, bHLHe73

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

liquid

mol wt

96 kDa

species reactivity

human, zebrafish

concentration

0.37 mg/mL

technique(s)

ChIP: suitable, western blot: 1:500-1:3000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... EPAS1(2034)

Immunogen

Recombinant fragment corresponding to a region within amino acids 74 and 376 of HIF2 alpha (Uniprot ID#Q99814)

Application

Suggested starting dilutions are as follows: WB: 1:500-1:3000, ChIP assay: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem/physiol Actions

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq]

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Warning

hcodes

Hazard Classifications

Aquatic Chronic 3 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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