SAB2702179
Anti-ERCC3 antibody produced in rabbit
Synonym(s):
GTF2H, RAD25, TFIIH, XPB
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
human
concentration
1 mg/mL
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: 1:500
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ERCC3(2071)
Immunogen
Peptide corresponding to the carboxy-terminus of human XPB.
Application
For WB: Use at a dilution of 1:500 and incubate at RT for 40 minutes. Blocking solution: 3% Milk/TBST at RT for one hour. Optimal dilutions/concentrations should be determined by the researcher.
Biochem/physiol Actions
The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne′s syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.
Features and Benefits
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Physical form
Phosphate-buffered saline, pH 7.2, containing no preservatives
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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