Skip to Content
Merck
CN

SAB4200589

Anti-WHAMM antibody produced in rabbit

affinity isolated antibody

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
human
Technique(s):
immunoblotting: 4-8 μg/mL using whole extracts of human U-2-OS cells.
Application:
Citations:
2
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

form

buffered aqueous solution

mol wt

antigen ~100 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

immunoblotting: 4-8 μg/mL using whole extracts of human U-2-OS cells.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... WHAMM(123720)

General description

WASP homologue associated with actin, membranes, and microtubules (WHAMM) is a nucleation promoting factor. It is expressed in the cis-Golgi and tubulo-vesicular membrane transport intermediates. WHAMM is composed of an N-terminal region, a coiled-coil region and a WCA region. It is located on the human chromosome at 15q25.2.

Immunogen

peptide corresponding to an internal region of human WHAMM ,conjugated to KLH. The corresponding sequence differs by 3 amino acids in mouse and by 4 in rat WHAMM.

Application

Anti-WHAMM antibody produced in rabbit may be used in immunoblotting.

Biochem/physiol Actions

Anti- WHAMM recognizes human WHAMM.
WASP homologue associated with actin, membranes, and microtubules (WHAMM) is involved in actin-related protein 2 & 3 (Arp2/3)-mediated actin polymerization, mediates Golgi membrane association and microtubule dynamics. It is also involved in Golgi structure maintenance and participates in vesicle transport between the endoplasmic reticulum and the Golgi complex.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Preparation Note

For continuous use, store at 2–8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Still not finding the right product?

or

Try our Product Selector Tool to narrow your options


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 1

Regulatory Information

新产品

This item has



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Seminars in cell & developmental biology
Seminars in Cell & Developmental Biology, 24(4), 258-266 (2013)
Kenneth G Campellone et al.
Cell, 134(1), 148-161 (2008-07-11)
The Arp2/3 complex is an actin nucleator that plays a critical role in many cellular processes. Its activities are regulated by nucleation-promoting factors (NPFs) that function primarily during plasma membrane dynamics. Here we identify a mammalian NPF called WHAMM (WASP



Global Trade Item Number

SKUGTIN
SAB4200589-200UL04061837725692