SAB4200632
Monoclonal Anti-ZBBX antibody produced in mouse
clone ZBX-7, purified from hybridoma cell culture
Synonym(s):
zinc finger B-box domain containing protein 1
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
shipped in
dry ice
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
ZBX-7, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
~1 mg/mL
technique(s)
flow cytometry: 5-10 μg/test using HeLa cells., immunoblotting: suitable, immunofluorescence: 2-4 μg/mL using MCF7 cells., immunohistochemistry: 20 μg/mL using human liver tissue sections.
isotype
IgG2a
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... ZBBX(79740)
General description
Monoclonal Anti-ZBBX (mouse IgG2a isotype) is derived from the hybridoma Zbx-7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. Zinc finger Bbox domain-containing protein 1 (ZBBX) is located on chromosome 3q26.1. It is a member of the B-box family.
Immunogen
synthetic peptide corresponding to an internal sequence of human ZBBX
Application
Monoclonal Anti-ZBBX antibody produced in mouse may be used in:
- immunoblotting
- flow cytometry
- immunofluorescence
- immunohistochemistry
Biochem/physiol Actions
Monoclonal Anti- ZBBX recognizes human ZBBX.
Zinc finger Bbox domain-containing protein 1 (ZBBX) number variations is associated with attention deficit hyperactivity disorder (ADHD), a common and persistent condition, which involves developmentally atypical and impairing inattention, impulsiveness and hyperactivity. It also functions as a tumor suppressor gene in hepatocellular carcinoma (HCC).
Physical form
Supplied as a solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as a preservative.
Preparation Note
For extended storage, freeze at -20 °C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Anath C Lionel et al.
Science translational medicine, 3(95), 95ra75-95ra75 (2011-08-13)
Attention deficit hyperactivity disorder (ADHD) is a common and persistent condition characterized by developmentally atypical and impairing inattention, hyperactivity, and impulsiveness. We identified de novo and rare copy number variations (CNVs) in 248 unrelated ADHD patients using million-feature genotyping arrays.
Lars Zender et al.
Journal of hepatology, 52(6), 921-929 (2010-04-14)
Hepatocellular carcinoma (HCC) is a deadly cancer, whose incidence is increasing worldwide. Albeit the main risk factors for HCC development have been clearly identified, such as hepatitis B and C virus infection and alcohol abuse, there is still preliminary understanding
Emma M Myers et al.
Methods (San Diego, Calif.), 73, 54-70 (2014-12-20)
Studies of the brain's transcriptome have become prominent in recent years, resulting in an accumulation of datasets with somewhat distinct attributes. These datasets, which are often analyzed only in isolation, also are often collected with divergent goals, which are reflected
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