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SAB4300140

Anti-phospho-PRKCQ (pSer695) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-MGC126514 antibody produced in rabbit, Anti-MGC141919 antibody produced in rabbit, Anti-PRKCT antibody produced in rabbit, Anti-nPKC-theta antibody produced in rabbit, Anti-protein kinase C, theta antibody produced in rabbit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~80 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100

isotype

IgG

immunogen sequence

(N-F-SP-F-M)

NCBI accession no.

NP_006248.1

UniProt accession no.

Q04759

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer695)

Gene Information

human ... PRKCQ(5588)

General description

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. Ref.8 PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

Immunogen

Peptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M), according to the protein PRKCQ.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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wgk

WGK 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
871511173

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