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Merck
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SAB4300240

Anti-phospho-KRT8 (pSer74) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CARD2 antibody produced in rabbit, Anti-CK8 antibody produced in rabbit, Anti-CYK8 antibody produced in rabbit, Anti-K2C8 antibody produced in rabbit, Anti-keratin 8 antibody produced in rabbit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~55 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(L-L-SP-P-L)

NCBI accession no.

NP_002264.1

UniProt accession no.

P05787

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer74)

Gene Information

human ... KRT8(3856)

General description

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Immunogen

Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L), according to the protein KRT8.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
951411307

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