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SAB4300317

Sigma-Aldrich

Anti-ATF2 (Ab-112 or 94) antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
Anti-CRE-BP1 antibody produced in rabbit, Anti-CREB2 antibody produced in rabbit, Anti-HB16 antibody produced in rabbit, Anti-MGC111558 antibody produced in rabbit, Anti-activating transcription factor 2 antibody produced in rabbit

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

65-75 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(D-L-S-P-L)

NCBI accession no.

NP_001871.2

UniProt accession no.

P15336

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ATF2(1386)

Immunogen

Peptide sequence around aa. 110-114 or 92-96 (D-L-S-P-L), according to the protein ATF2.

Features and Benefits

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Target description

Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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