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Merck
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SAB4300440

Anti-NFKBIA (Ab-42) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-IKBA antibody produced in rabbit, Anti-MAD-3 antibody produced in rabbit, Anti-NFKBI antibody produced in rabbit, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD01633603
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p), WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~39 kDa

species reactivity

human, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(E-E-Y-E-Q)

NCBI accession no.

NP_065390.1

UniProt accession no.

P25963

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NFKBIA(4792)

Related Categories

General description

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

Immunogen

Peptide sequence around aa. 40-44 (E-E-Y-E-Q), according to the protein NFKBIA.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
871521176

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