Anti-PRKAA1/PRKAA2 (Ab-174/172) antibody produced in rabbit

Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.

Peptide sequence around aa. 172-176/170-174 (L-R-T-S-C), according to the proteins PRKAA1/PRKAA2.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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