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Merck
CN

SAB4300631

Anti-phospho-Ephrin-B2 (pTyr316) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-EPLG5, Anti-HTKL, Anti-Htk-L, Anti-LERK5

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-phospho-Ephrin-B2 (pTyr316) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~37 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(P-V-Yp-I-V)

NCBI accession no.

NM_004093.2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr316)

Quality Level

100

Gene Information

human ... SEPTIN1(1948)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

The antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5′ UTR but that encode the same protein have been identified for this gene.

Immunogen

Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Yp-I-V), according to the protein NP_004084.1

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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