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SAB4300962

Anti-GIP antibody produced in rabbit

affinity isolated antibody

Synonym(s):

GIP, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
5
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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

17 kDa

species reactivity

human

concentration

0.5 mg/mL

technique(s)

immunohistochemistry: 1:10- 1:50, western blot: 1:200-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_004114.1

UniProt accession no.

P09681

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GIP(2695)

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General description

Glucose-dependent insulinotropic polypeptide (GIP) or gastric inhibitory polypeptide is a 42-amino acid gastrointestinal regulatory peptide, expressed in K cells of the small intestine and in cells of the submandibular salivary gland. The gene encoding GIP is localized on human chromosome 17.

Immunogen

Fusion protein corresponding to a region derived from internal residues of human gastric inhibitory polypeptide

Biochem/physiol Actions

In the presence of glucose, glucose-dependent insulinotropic polypeptide (GIP) induces insulin secretion. It acts as an antagonist of the human GIP receptor. Aberrations in GIP are associated with visceral fat accumulation. The protein has been studied to have a protective function in obesity and atherosclerosis.
The antibody detects endogenous levels of total GIP protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

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Certificates of Analysis (COA)

Lot/Batch Number
492635756

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Rs46522 in the Ubiquitin-Conjugating Enzyme E2Z Gene Is Associated with the Risk of Coronary Artery Disease in Individuals of Chinese Han Population with Type 2 Diabetes.
Lu D, et al.
Journal of Diabetes Research (2017)
The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor.
Asmar M, et al.
Diabetes (2017)
Incretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis.
Srivastava S, et al.
Biomedicine and Pharmacotherapy, 97, 330-338 (2018)
Common variants of GIP are associated with visceral fat accumulation in Japanese adults.
Nakayama K, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 307(11), G1108-G1114 (2014)
Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line.
Boylan MO, et al.
The Journal of Biological Chemistry, 272(28), 17438-17443 (1997)

Global Trade Item Number

SKUGTIN
SAB4300962-100UL04061837445637

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