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SAB4301534

Sigma-Aldrich

Anti-phospho-p38 MAPK (pTyr322) antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
CSBP, EXIP, Mxi2, RK, p38
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

43 kDa

species reactivity

mouse, human

concentration

1.0 mg/mL

technique(s)

western blot: 1:500-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_001306.1 

UniProt accession no.

Q16539

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr322)

Gene Information

human ... MAPK14(1432)

Specificity

The antibody detects endogenous level of p38 MAPK only when phosphorylated at Tyrosine 322.

Immunogen

Peptide sequence around phosphorylation site of Tyrosine 322(D-P-Y(p)-D-Q) derived from Human p38 MAPK.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Ming-Wei Liu et al.
International journal of molecular medicine, 38(5), 1419-1432 (2016-09-27)
Xuebijing injection (XBJ) has long been used to treat infectious diseases in China. The therapeutic effect of XBJ is probably associated with anti-inflammatory effects. However, the precise mechanisms responsible for the effects of XBJ remain unknown. The present study was conducted
Miaoqing Ye et al.
Environmental toxicology, 39(2), 551-561 (2023-07-12)
The mechanisms underlying the progression of non-alcoholic fatty liver disease (NAFLD) into hepatocellular carcinoma (HCC) remains confusing and the therapeutics approaches are also challenging. Here, we aimed to investigate the effects of scoparone on the treatment of HCC stemmed from
Chin-Feng Hsuan et al.
Molecules (Basel, Switzerland), 25(24) (2020-12-17)
The proliferation and migration of vascular smooth muscle cells (VSMCs) are essential in the pathogenesis of various vascular diseases, such as atherosclerosis and restenosis. Among the mediators of VSMC during atherosclerosis development, platelet-derived growth factor (PDGF)-BB is a potent mitogen
Zhihai Yuan et al.
Journal of biochemical and molecular toxicology, 36(9), e23138-e23138 (2022-07-16)
Glioma is the foremost recurrent type of brain tumor in humans; in particular, glioblastoma (GBM) is the main form of brain tumor (GBM) that is highly proliferative and impervious to apoptosis. Triphlorethol-A (TA), a phlorotannin isolated from Ecklonia cava, exhibited cytoprotective, antioxidant, and anticancer properties. However
Chunhua Wang et al.
Molecular medicine reports, 16(1), 922-928 (2017-06-01)
In the present study, the protective effect and the potential underlying mechanism of rutaecarpine (Ru) on renal ischemia reperfusion injury (IRI) in rats were investigated. A renal ischemia reperfusion mouse model was established. Ru at 30, 60 mg/kg administered intraperitoneally prior
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