SAB4500169
Anti-CD3EAP antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-sense to ERCC-1 protein, ASE-1, CD3-ε-associated protein, DNA-directed RNA polymerase I subunit RPA34, RNA polymerase I-associated factor PAF49
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 54 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, western blot: 1:500-1:1000
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RPA34(10849)
General description
The CD3EAP (CD3e molecule, epsilon-associated protein) gene is mapped to human chromosome 19q13.3. It encodes a DNA-dependent RNA polymerase I subunit RPA34 (replication protein A34). This protein is localized to the nucleolus, in the fibrillar centers during interphase and the nucleolus organizer regions of the chromosomes during cell division. Anti-CD3EAP antibody detects endogenous levels of total CD3EAP protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD3EAP.
Immunogen Range: 441-490
Immunogen Range: 441-490
Biochem/physiol Actions
The CD3EAP (CD3e molecule, epsilon-associated protein) gene participates in the process of programmed cell death and ribosomal RNA transcription. CD3EAP expression is implicated in the pathogenesis of non-small cell lung cancer (NSCLC).
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
Effects of PPP1R13L and CD3EAP variants on lung cancer susceptibility among nonsmoking Chinese women
Yin J, et al.
Gene, 524(2), 228-231 (2013)
19p13. 3-GADD45B common variants and 19q13. 3-PPP1R13L and 19q13. 3-CD3EAP in lung cancer risk among Chinese
Hou W, et al.
Chemico-Biological Interactions, 277, 74-78 (2017)
Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment
Zhang G, et al.
International Journal of Oncology, 52(6), 2155-2165 (2018)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4500169-100UG | 04061835710010 |