SAB4502905
Anti-Synapsin, N-Terminal antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Brain protein 4.1, SYN-1, synapsin I
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 74 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SYN1(6853)
General description
Anti-Synapsin Antibody detects endogenous levels of total Synapsin protein.
Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. The protein is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. SYN1 gene is located in human chromosome Xp11.3.
Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. The protein is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. SYN1 gene is located in human chromosome Xp11.3.
Immunogen
The antiserum was produced against synthesized peptide derived from human Synapsin.
Immunogen Range: 3-52
Immunogen Range: 3-52
Application
Anti-Synapsin, N-Terminal antibody has been used in immunohistochemistry.
Biochem/physiol Actions
Synapsin I (SYN1) plays an important role in neurotransmitter release, exocytosis of the synaptic vesicles, neurite elongation and synaptogenesis. Brain dysfunction occurs due to improper expression of synapsin I.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
A novel method to derive and expand mice neural stem cells efficiently without neuro-sphere formation.
Ma ZZ, et al.
International Journal of Clinical and Experimental Medicine, 8(8), 12834?12841-12834?12841 (2015)
Increased synapsin I expression in cerebral malaria.
Thonsranoi K, et al.
International Journal of Clinical and Experimental Pathology, 8(11), 13996?14004-13996?14004 (2015)
Evidence for a Turner syndrome locus or loci at Xp11. 2-p22. 1.
Zinn AR, et al.
American Journal of Human Genetics, 63(6), 1757-1766 (1998)
Zhi-Zhao Ma et al.
International journal of clinical and experimental medicine, 8(8), 12834-12841 (2015-11-10)
Neural stem cells (NSCs) are multi-potent stem cells able to self-renew and generate immature and differentiated cell populations by asymmetric division. The NSCs are of considerable interest for cell replacement in neuro-degenerative diseases. NSCs are usually identified and expanded by
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service