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Merck
CN

SAB4502926

Anti-TBP antibody produced in rabbit

affinity isolated antibody

Synonym(s):

TATA binding factor, TATA sequence-binding protein, TATA-box binding protein, TATA-box factor, TFIID

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD01634214
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
4

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 37 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000, western blot: 1:500-1:1000

NCBI accession no.

P20226

UniProt accession no.

P20226

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TBP(6908)

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General description

Anti-TBP antibody detects endogenous levels of total TBP protein.
The TBP (TATA-binding protein) gene is mapped to human chromosome 6q27.

Immunogen

The antiserum was produced against synthesized peptide derived from human TBP.

Immunogen Range: 151-200

Biochem/physiol Actions

The TBP (TATA-binding protein) gene encodes a subunit of TFIIIB (transcription factor IIIB) complex and recognizes the TATA box in the DNA. It thus, plays an important role in RNA polymerase II transcription machinery. TBP is known to induce stress granule formation in hepatitis B viral infection.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料
常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
3110435

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Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly.
Tsai KN
Journal of Virology, 89(22), 11406-11419 (2015)
The Pathogenic Role of Low Range Repeats in SCA17.
Shin JH
PLoS ONE, 10(8), 1-10 (2015)
Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID.
Malecova B
Transcription, 6(2), 21-32 (2015)
Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Gouge J
Nature Communications, 8(1):130, 1-11 (2017)

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