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Merck
CN

SAB4700299

Monoclonal Anti-HLA-A2-PE antibody produced in mouse

clone BB7.2, purified immunoglobulin, buffered aqueous solution

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
phycoerythrin (R-PE) conjugate
Clone:
BB7.2, monoclonal
Application:
FACS
Citations:
3
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biological source

mouse

conjugate

phycoerythrin (R-PE) conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

BB7.2, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

flow cytometry: suitable

isotype

IgG2b

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... HLA-A(3105)

General description

Human leukocyte antigen A α-chain (HLA-A2) is encoded by the gene mapped to human chromosome 6p22.1. HLA-A belongs to the class I molecules of HLa family. The protein structure consists of two polypeptide chains, heavy chain and the non-covalently attached light chain.
The antibody BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.

The previously assigned protein identifier P01891 has been merged into P04439. Full details can be found on the UniProt database.

Immunogen

HLA-A2 solubilized by papain

Application

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Biochem/physiol Actions

Human leukocyte antigen A α-chain (HLA-A2) plays a major role in peptide antigen presentation. The encoded protein interacts with cytotoxic T cells (CTL) and facilitates the identification of peptide derived from the influenza matrix protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料
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Structure of the human class I histocompatibility antigen, HLA-A2.
Bjorkman PJ
Nature, 329, 506-512 (1987)
Modern vitiligo genetics sheds new light on an ancient disease
Spritz RA
The Journal of Dermatology, 40, 310-318 (2013)
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2
Gotch F
Nature, 326, 881-882 (1987)

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