SAB4700552
Monoclonal Anti-Cd3e antibody produced in hamster
clone 145-2C11, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-CD3
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
biological source
hamster
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
145-2C11, monoclonal
form
buffered aqueous solution
species reactivity
mouse
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
mouse ... Cd3e(12501)
General description
The hamster monoclonal antibody 145-2C11 reacts with mouse CD3 (epsilon subunit). This antibody is commonly used as a phenotypic marker for mouse T cells.
Immunogen
Mouse BM10-37 cytotoxic T lymphocytes
Application
The reagent is designed for Flow Cytometry analysis using 1-2 μg reagent / 1e6 cells in a suspension.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Susanne M A Lens et al.
Molecular and cellular biology, 22(15), 5419-5433 (2002-07-09)
The caspase 8 inhibitor c-FLIP(L) can act in vitro as a molecular switch between cell death and growth signals transmitted by the death receptor Fas (CD95). To elucidate its function in vivo, transgenic mice were generated that overexpress c-FLIP(L) in
Lisa A Pitcher et al.
European journal of immunology, 35(12), 3643-3654 (2005-11-01)
T cell receptor (TCR) signal transduction is mediated by the immunoreceptor tyrosine-based activation motifs (ITAM). The ten ITAM in the TCR complex are distributed in two distinct signaling modules termed TCR zetazeta and CD3 gammaepsilon/deltaepsilon. To delineate the specific role
M Hanief Sofi et al.
Molecular immunology, 46(7), 1443-1450 (2009-02-03)
T helper (Th) cell differentiation is a key event to mount an appropriate immune response. Th1 and Th2 cells produce their signature cytokines IFN-gamma and IL-4, respectively. However, as we have reported, CD4 T cells selected by MHC class II-expressing
Qizhi Tang et al.
Journal of immunology (Baltimore, Md. : 1950), 168(9), 4480-4487 (2002-04-24)
FcR nonbinding anti-CD3 epsilon mAbs elicit partial TCR signaling that leads to T cell unresponsiveness and tolerance in vivo. In this study, the membrane-proximal events that promote T cell inactivation by FcR nonbinding anti-CD3 mAbs were examined. In the context
Joshua C Cyktor et al.
Infection and immunity, 81(4), 1090-1099 (2013-01-24)
The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1
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