SAB5300248
Monoclonal Anti-MMP9 antibody produced in mouse
clone 5C3, ascites fluid
Synonym(s):
CLG4B, GELB, MANDP2, MMP-9
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5C3, monoclonal
Application:
ELISA (d), FACS, WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
5C3, monoclonal
mol wt
92 kDa
species reactivity
human
technique(s)
direct ELISA: 1:10,000, flow cytometry: 1:200-1:400, western blot: 1:500-1:2,000
isotype
IgG2a
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MMP9(4318)
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General description
Matrix metalloproteinase 9 (MMP-9) is also known as gelatinase-B and collagenase type IV-B. It is a proteinase. MMP9 is located on human chromosome 20q13.2.
Immunogen
Purified recombinant fragment of human MMP9 expressed in E.coli.
Mouse monoclonal antibody raised against MMP9
Mouse monoclonal antibody raised against MMP9
Biochem/physiol Actions
Matrix metalloproteinase 9 (MMP-9) regulates inflammatory mediators. It plays a major role in the degradation of extracellular matrix (ECM) components, the formation of chemokine gradients, the generation of reactive oxygen species and the movement of effector cells. It stimulates the progression of autoimmune neo-epitopes. MMP-9 is present at high level in the saliva and tear fluid of patients with Sjoogren′s syndrome.
Physical form
Ascitic fluid containing 0.03% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
动植物来源生物产品
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Matrix metalloproteinase 9 (MMP-9) gene polymorphism and MMP-9 plasma levels in primary Sjogren's syndrome
Hulkkonen J, et al.
Rheumatology (Basel), 43(12), 1476-1479 (2004)
Ureaplasma isolates stimulate pro-inflammatory CC chemokines and matrix metalloproteinase-9 in neonatal and adult monocytes
Glaser, et al.
PLoS ONE, 13(3), e0194514-e0194514 (2018)
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