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Merck
CN

SAB5500062

Sigma-Aldrich

Anti-CD35 antibody, Rabbit monoclonal

clone SP197, recombinant, expressed in proprietary host, affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP197, monoclonal

species reactivity

human (tested)

technique(s)

immunoblotting: 1:400
immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... CR1(1378)

General description

CD35, also known as complement receptor type 1, is a monomeric single-pass type 1 membrane glycoprotein from complement activation (RCA) family. CD35 binds complement components C3b and C4b and has an inhibitory effect on complement activation by both the classical and alternative pathways. CD35 is expressed by glomerular podocytes, follicular dendritic cells, erythrocytes, and some leukocytes. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus.

Immunogen

Synthetic peptide derived from human CD35 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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