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Merck
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SAB5600114

Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin

Synonym(s):

Platelet-derived growth factor receptor beta

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM303, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunohistochemistry: 1:500-1:1000
western blot: 1:250-1:500

isotype

IgG

NCBI accession no.

5159

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PDGFRB(5159)

Biochem/physiol Actions

PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.

Immunogen

A peptide corresponding to the C-terminus of human CD140b.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
Q1101330
Q0601066

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A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer.
Staub E, et al.
Molecular Cancer, 5(1), 37-37 (2006)
Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Liu F
Oncotarget, 8(13), 22059-22075 (2017)
PDGFRB gain-of-function mutations in sporadic infantile myofibromatosis.
Arts FA
Human Molecular Genetics, 26(10), 1801-1810 (2017)

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