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Merck
CN

SAB5600233

Anti-Acetyl-Histone H3 (Lys18) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM166, purified immunoglobulin

Synonym(s):

H3K18ac, Histone H3 (acetyl K18)

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About This Item

NACRES:
NA.43
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-Acetyl-Histone H3 (Lys18) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM166, purified immunoglobulin

recombinant

expressed in HEK 293 cells

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM166, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

vertebrates

technique(s)

ChIP: 2-10 μg/mL
ELISA: 0.5-2 μg/mL
immunocytochemistry: 0.5-2 μg/mL
immunohistochemistry: 1—10 μg/mL
multiplexing: 0.1-0.5 μg/mL
western blot: 0.5— 2 μg/mL

isotype

IgG

NCBI accession no.

8350

UniProt accession no.

P84243

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

acetylation (Lys18)

Gene Information

human ... H3C1(8350)

Biochem/physiol Actions

This antibody reacts to Histone H3 acetylated at Lysine 18 (K18ac). No cross reactivity with other acetylated Lysines in histone H3.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

An acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys18)

Physical form

Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
S0302099

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Yanhua Zhao et al.
Cellular and molecular life sciences : CMLS, 81(1), 298-298 (2024-07-12)
In spite of its essential role in culture media, the precise influence of lactate on early mouse embryonic development remains elusive. Previous studies have implicated lactate accumulation in medium affecting histone acetylation. Recent research has underscored lactate-derived histone lactylation as

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