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Merck
CN

SAB5600251

Anti-N6-Methyladenosine (m6A) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM362, purified immunoglobulin

Synonym(s):

m6A

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-N6-Methyladenosine (m6A) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM362, purified immunoglobulin

recombinant

expressed in HEK 293 cells

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM362, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

vertebrates, human

technique(s)

ELISA: 0.1-3 μg/mL
dot blot: 0.5-2 μg/mL
immunocytochemistry: 0.1— 3 μg/mL
immunoprecipitation (IP): .2-5 μg/mL (Methylated RNA)

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... METTL3(56339)

Biochem/physiol Actions

This antibody reacts to N6-Methyladenosine (m6A) in both RNA and DNA. No cross reactivity with non-methylated adenosine.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

BSA-conjugated N6-Methyladenosine

Physical form

Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

含少量动物源组分生物产品
常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
X1107287
U1104783
S0202089

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Shuai Ren et al.
Annals of translational medicine, 11(1), 15-15 (2023-02-11)
Keloid is a dermal fibrotic disease characterized by excessive proliferation of dermal fibroblasts and deposition of excessive collagen. N6-methyladenosine (m6A) plays a significant role in numerous physiological and pathological regulatory processes in the human body. Fat mass and obesity-associated protein
Fang Wang et al.
Chinese medicine, 18(1), 122-122 (2023-09-22)
Curdione is a sesquiterpene isolated from Curcumae Rhizoma that possesses high biological activity and extensive pharmacological effects. As a traditional Chinese medicine, Curcumae Rhizoma can inhibit the development of many types of cancer, especially colorectal cancer. However, the anti-colorectal mechanism
Yufan Ying et al.
Molecular cancer, 23(1), 79-79 (2024-04-25)
R-loops are prevalent three-stranded nucleic acid structures, comprising a DNA-RNA hybrid and a displaced single-stranded DNA, that frequently form during transcription and may be attributed to genomic stability and gene expression regulation. It was recently discovered that RNA modification contributes

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