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Merck
CN

SAB5700210

Anti-Acetyl-Histone H4-K16 antibody produced in rabbit

Synonym(s):

FO108, H4, H4/n, H4F2, H4FN, HIST1H4A, HIST2H4, HIST2H4A, Histone H4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

11

species reactivity

mouse, human, rat

concentration

0.43 mg/ml

technique(s)

ChIP: 1:50-1:200
immunofluorescence: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

P62805

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

acetylation (Lys16)

Gene Information

human ... H4C14(8370)

General description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Immunogen

A synthetic acetylated peptide around K16 of human Histone H4 (NP_001029249.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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