SAB5700942
Anti-APEX1/APE1 antibody produced in rabbit
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About This Item
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IHC, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody product type
primary antibodies
clone
monoclonal
form
liquid
species reactivity
mouse, human, rat
concentration
0.35 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... APEX1(328)
General description
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
Immunogen
A synthesized peptide derived from human APEX1/APEX1/APE1
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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