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Merck
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SAB5700942

Anti-APEX1/APE1 antibody produced in rabbit

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About This Item

NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody product type

primary antibodies

clone

monoclonal

form

liquid

species reactivity

mouse, human, rat

concentration

0.35 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... APEX1(328)

General description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide derived from human APEX1/APEX1/APE1

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Global Trade Item Number

SKUGTIN
SAB5700942-100UL04065267659169