SAB5701873
Anti-Phospho-ATF2-T71 antibody produced in rabbit
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
monoclonal
Species reactivity:
mouse, human, rat
Application:
IHC, WB
Citations:
-
biological source
rabbit
antibody product type
primary antibodies
clone
monoclonal
form
liquid
species reactivity
mouse, human, rat
concentration
0.52 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pThr71)
Quality Level
Gene Information
human ... ATF2(1386)
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General description
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
Immunogen
A phospho specific peptide corresponding to residues surrounding T71 of human ATF2
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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